Structure of PDB 5yb0 Chain I

Receptor sequence
>5yb0I (length=336) Species: 5759 (Entamoeba histolytica) [Search protein sequence]
IHNFGAGPAAMAKEVIEATAKAVNNFWEGLSILEISHRSKEWINVMNETK
ALMKEVMDIPEGYEILFFGGGASLQFLMVAMNLLNKKACYLDTGVWASKA
IKEAENIGEVKIIGTSKDKNYTYIPEYQIPSDYDYFHITTNNTIYGTEIR
KDIESPIPLVADMSSDILSKPIDISKYSLIYAGAQKNCGAAGVTIVIIKK
EILGKVQRKIPIILDYQVHILNNSMYNTPPVISIFTVNQTLKYIKKIGGL
KKIQELNEEKARLLYAEIDRNKIFRGTVRKKDRSIMNVCFSEYALQKGII
GIKGHRSVGGFRASIYNAVTIESVQALIKCMHDFEQ
3D structure
PDB5yb0 N-terminal residues are crucial for quaternary structure and active site conformation for the phosphoserine aminotransferase from enteric human parasite E. histolytica.
ChainI
Resolution2.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.6.1.52: phosphoserine transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP I G76 A77 S78 F81 W101 T148 S169 K191 G71 A72 S73 F76 W96 T143 S164 K186
Gene Ontology
Molecular Function
GO:0004648 O-phospho-L-serine:2-oxoglutarate aminotransferase activity
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0006563 L-serine metabolic process
GO:0006564 L-serine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5yb0, PDBe:5yb0, PDBj:5yb0
PDBsum5yb0
PubMed30959130
UniProtQ60I38

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