Structure of PDB 5vk1 Chain I

Receptor sequence
>5vk1I (length=82) Species: 9606 (Homo sapiens) [Search protein sequence]
QVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDAAAQHMVY
CGGDLLGELLGRQSFSVKDPSPLYDMLRKNLV
3D structure
PDB5vk1 Dithiocarbamate-inspired side chain stapling chemistry for peptide drug design.
ChainI
Resolution2.69 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide I V92 K93 V67 K68
BS02 peptide I M53 L56 G57 I60 M61 Y66 Q71 H72 V92 P95 M28 L31 G32 I35 M36 Y41 Q46 H47 V67 P70
Gene Ontology
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5vk1, PDBe:5vk1, PDBj:5vk1
PDBsum5vk1
PubMed30809370
UniProtO15151|MDM4_HUMAN Protein Mdm4 (Gene Name=MDM4)

[Back to BioLiP]