Structure of PDB 5mp9 Chain I

Receptor sequence
>5mp9I (length=385) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
TRCKLKLLRMERIKDHLLLEEEFVSNSEILKPFEKKQEEEKKQLEEIRGN
PLSIGTLEEIIDDDHAIVTSPTMPDYYVSILSFVDKELLEPGCSVLLHHK
TMSIVGVLQDDADPMVSVMKMDKSPTESYSDIGGLESQIQEIKESVELPL
THPELYEEMGIKPPKGVILYGAPGTGKTLLAKAVANQTSATFLRIVGSEL
IQKYLGDGPRLCRQIFKVAGENAPSIVFIDEIDAIGTKRYDSNSGGEREI
QRTMLELLNQLDGFDDRGDVKVIMATNKIETLDPALIRPGRIDRKILFEN
PDLSTKKKILGIHTSKMNLSEDVNLETLVTTKDDLSGADIQAMCTEAGLL
ALRERRMQVTAEDFKQAKERVMKNKVEENLEGLYL
3D structure
PDB5mp9 Structural insights into the functional cycle of the ATPase module of the 26S proteasome.
ChainI
Resolution4.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP I P225 G226 G228 K229 T230 L231 G389 Q393 P173 G174 G176 K177 T178 L179 G337 Q341
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0036402 proteasome-activating activity
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0010604 positive regulation of macromolecule metabolic process
GO:0031503 protein-containing complex localization
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043171 peptide catabolic process
GO:0045732 positive regulation of protein catabolic process
GO:0070651 nonfunctional rRNA decay
GO:0070682 proteasome regulatory particle assembly
GO:1901800 positive regulation of proteasomal protein catabolic process
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0008540 proteasome regulatory particle, base subcomplex

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Molecular Function
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Cellular Component
External links
PDB RCSB:5mp9, PDBe:5mp9, PDBj:5mp9
PDBsum5mp9
PubMed28115689
UniProtP40327|PRS4_YEAST 26S proteasome regulatory subunit 4 homolog (Gene Name=RPT2)

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