Structure of PDB 5jul Chain I

Receptor sequence
>5julI (length=1233) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
HQYQYKDILSVFEDAFVDNFDCKDVQDMPKSILSKEEIDHIIMSKDAVSG
TLRLFWTLLSKQEEMVQKFVEEVLRINYKFLMSPIKTEQRQPSMMTRMYI
EQRDRLYNDNQVFAKYNVSRLQPYLKLRQALLELRPAKNVLIDGVLGSGK
TWVALDVCLSYKVQCKMDFKIFWLNLKNCNSPETVLEMLQKLLYQIDPNW
TSRSDHSSNIKLRIHSIQAELRRLLKSKPYENCLLVLLNVQNAKAWNAFN
LSCKILLTTRFKQVTDFLSAATTTHISLDHHSMTLTPDEVKSLLLKYLDC
RPQDLPREVLTTNPRRLSIIAESIRDGLATWDNWKHVNCDKLTTIIESSL
NVLEPAEYRKMFDRLSVFPPSAHIPTILLSLIWFDVIKSDVMVVVNKLHK
YSLVEKQPKESTISIPSIYLELKVKLENEYALHRSIVDHYNIPKTFDSDD
LIPPYLDQYFYSHIGHHLKNIEHPERMTLFRMVFLDFRFLEQKIRHDSTA
WNASGSILNTLQQLKFYKPYICDNDPKYERLVNAILDFLPKIEENLICSK
YTDLLRIALMAEDEAIFEEAHKQVQRFDDRVWFTNHGRFHQHRQIINLGD
NEGRHAVYLHNDFCLIALASGQILLTDVSLEGEDTYLLRDESDSSDILRM
AVFNQQKHLITLHCNGSVKLWSLWPNSVVKRFIGSYANLKIVAFYLNEDA
GLIQLHVAFINGDVSILNWDEQDQEFKLSHVPVLKTMQSGIRCFVQVLKR
YYVVCTSNCTLTVWDLTNGSSNTLELHVFNVENDTPLALDVFDERSKTAT
VLLIFKYSVWRLNFLPGLSVSLQSEAVGSFITCGKRSTDGRYLLLGTSEG
LIVYDLKISDPVLRSNVSEHIECVDIYELFDPVYKYIVLCGAKGKQVVHV
HTLRSVSGSNSHQNREIAWVHSADEISVMTKACLEPNVYLRSLMDMTRER
TQLLAVDSKERIHLIKPAISRISEWSTITPTHAASNCKINAISAFNDEQI
FVGYVDGVIIDVIHDTALPQQFIEEPIDYLKQVSPNILVASAHSAQKTVI
FQLEKIDPLQPNDQWPLMMDVSTKYASLQEGQYIILFSDHGVCHLDIANP
SAFVKPKDSEEYIVGFDLKNSLLFLAYENNIIDVFRLIFSCNQLRYEQIC
EEEIAQKAKISYLVATDDGTMLAMGFENGTLELFAVENRKVQLIYSIEEV
HEHCIRQLLFSPCKLLLISCAEQLCFWNVTHMR
3D structure
PDB5jul A Near-Atomic Structure of the Dark Apoptosome Provides Insight into Assembly and Activation.
ChainI
Resolution4.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DTP I N124 G154 G156 K157 T158 W159 R267 L300 P321 R322 N117 G147 G149 K150 T151 W152 R260 L293 P314 R315
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0042802 identical protein binding
GO:0043531 ADP binding
GO:0050700 CARD domain binding
Biological Process
GO:0002921 negative regulation of humoral immune response
GO:0006915 apoptotic process
GO:0007291 sperm individualization
GO:0010332 response to gamma radiation
GO:0012501 programmed cell death
GO:0021556 central nervous system formation
GO:0022416 chaeta development
GO:0033353 S-adenosylmethionine cycle
GO:0034352 positive regulation of glial cell apoptotic process
GO:0035006 melanization defense response
GO:0035070 salivary gland histolysis
GO:0042594 response to starvation
GO:0043065 positive regulation of apoptotic process
GO:0046672 positive regulation of compound eye retinal cell programmed cell death
GO:0048102 autophagic cell death
GO:0048813 dendrite morphogenesis
GO:0070050 neuron cellular homeostasis
GO:0070328 triglyceride homeostasis
GO:1901053 sarcosine catabolic process
GO:1904747 positive regulation of apoptotic process involved in development
Cellular Component
GO:0005829 cytosol
GO:0043293 apoptosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5jul, PDBe:5jul, PDBj:5jul
PDBsum5jul
PubMed27916517
UniProtQ7KLI1

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