Structure of PDB 5hyj Chain I

Receptor sequence
>5hyjI (length=193) Species: 9606 (Homo sapiens) [Search protein sequence]
KEVEQDPGPLSVPEGAIVSLNCTYSNSAFQYFMWYRQYSRKGPELLMYTY
SSGNKEDGRFTAQVDKSSKYISLFIRDSQPSDSATYLCAMRGDSSYKLIF
GSGTRLLVRPDIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDS
DVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIP
3D structure
PDB5hyj A "hotspot" for autoimmune T cells in type 1 diabetes.
ChainI
Resolution3.06 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide I D94 S96 Y97 D93 S95 Y96
Gene Ontology
Molecular Function
GO:0042605 peptide antigen binding
Biological Process
GO:0002250 adaptive immune response
Cellular Component
GO:0005886 plasma membrane
GO:0042101 T cell receptor complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5hyj, PDBe:5hyj, PDBj:5hyj
PDBsum5hyj
PubMed27183386
UniProtA0A0B4J271;
P01848|TRAC_HUMAN T cell receptor alpha chain constant (Gene Name=TRAC)

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