Structure of PDB 5ews Chain I

Receptor sequence
>5ewsI (length=131) Species: 9606 (Homo sapiens) [Search protein sequence]
MTGELEVKNMDMKPGSTLKITGSIADGTDGFVINLGQGTDKLNLHFNPRF
SESTIVCNSLDGSNWGQEQREDHLCFSPGSEVKFTVTFESDKFKVKLPDG
HELTFPNRLGHSHLSYLSVRGGFNMSSFKLK
3D structure
PDB5ews Human galectin-2 interacts with carbohydrates and peptides non-classically: new insight from X-ray crystallography and hemagglutination.
ChainI
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC I R52 E71 R73 R49 E68 R70
BS02 GAL I H48 R52 N61 E71 H45 R49 N58 E68
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016936 galactoside binding
GO:0030246 carbohydrate binding
Biological Process
GO:0043029 T cell homeostasis
GO:0043065 positive regulation of apoptotic process
GO:0050729 positive regulation of inflammatory response
GO:0098609 cell-cell adhesion
Cellular Component
GO:1990724 galectin complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5ews, PDBe:5ews, PDBj:5ews
PDBsum5ews
PubMed27563008
UniProtP05162|LEG2_HUMAN Galectin-2 (Gene Name=LGALS2)

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