Structure of PDB 5c0a Chain I

Receptor sequence
>5c0aI (length=197) Species: 9606 (Homo sapiens) [Search protein sequence]
EVEQDPGPLSVPEGAIVSLNCTYSNSAFQYFMWYRQYSRKGPELLMYTYS
SGNKEDGRFTAQVDKSSKYISLFIRDSQPSDSATYLCAMRGDSSYKLIFG
SGTRLLVRPDIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSD
VYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFF
3D structure
PDB5c0a Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
ChainI
Resolution2.46 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide I D94 Y97 D92 Y95
Gene Ontology
Molecular Function
GO:0042605 peptide antigen binding
Biological Process
GO:0002250 adaptive immune response
Cellular Component
GO:0005886 plasma membrane
GO:0042101 T cell receptor complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5c0a, PDBe:5c0a, PDBj:5c0a
PDBsum5c0a
PubMed27183389
UniProtA0A0B4J271;
P01848|TRAC_HUMAN T cell receptor alpha chain constant (Gene Name=TRAC)

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