Structure of PDB 4z25 Chain I

Receptor sequence
>4z25I (length=649) Species: 212035 (Acanthamoeba polyphaga mimivirus) [Search protein sequence]
NLTGDIVIIGAGAAGSLLAHYLARFSNMKIILLEAGHSHFNDPVVTDPMG
FFGKYNPPNENISMSQNPSYSWQGAQEPNTGAYGNRPIIAHGMGFGGSTM
INRLNLVVGGRTVFDNDWPVGWKYDDVKNYFRRVLVDINPVRDNTKASIT
SVALDALRIIAEQQIASGEPVDFLLNKATGNVPNVEKTTPDAVPLNLNDY
EGVNSVVAFSSFYMGVNQLSDGNYIRKYAGNTYLNRNYVDENGRGIGKFS
GLRVVSDAVVDRIIFKGNRAVGVNYIDREGIMHYVKVNKEVVVTSGAFYT
PTILQRSGIGDFTYLSSIGVKNLVYNNPLVGTGLKNHYSPVTITRVHGEP
SEVSRFLSNMAANPTNMGFKGLAELGFHRLDPNKPANANTVTYRKYQLMM
TAGVGIPAEQQYLSGLSPSSNNLFTLIADDIRFAPEGYIKIGTPNIPRDV
PKIFFNTFVTYTPTSAPADQQWPIAQKTLAPLISALLGYDIIYQTLMSMN
QTARDSGFQVSLEMVYPLNDLIYKLHNGLATYGANWWHYFVPTLVGDDTP
AGREFADTLSKLSYYPRVGAHLDSHQGCSCSIGRTVDSNLKVIGTQNVRV
ADLSAAAFPPGGNTWATASMIGARAVDLILGFPYLRDLPVNDVPILNVN
3D structure
PDB4z25 A Mimivirus Enzyme that Participates in Viral Entry.
ChainI
Resolution3.339 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R358 D432 D576 H578 G615 N616
Catalytic site (residue number reindexed from 1) R355 D429 D573 H575 G612 N613
Enzyme Commision number 1.-.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FAD I G13 G15 A16 A17 E37 A38 W75 G95 M96 G100 S101 I104 N105 R106 L107 N108 V263 S298 S577 H578 L606 N616 T617 W618 G10 G12 A13 A14 E34 A35 W72 G92 M93 G97 S98 I101 N102 R103 L104 N105 V260 S295 S574 H575 L603 N613 T614 W615
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0042802 identical protein binding
GO:0050660 flavin adenine dinucleotide binding
Cellular Component
GO:0016020 membrane
GO:0033644 host cell membrane
GO:0044423 virion component

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:4z25, PDBe:4z25, PDBj:4z25
PDBsum4z25
PubMed25982526
UniProtQ5UPL2|YR135_MIMIV Putative GMC-type oxidoreductase R135 (Gene Name=MIMI_R135)

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