Structure of PDB 4xrs Chain I

Receptor sequence
>4xrsI (length=56) Species: 9606 (Homo sapiens) [Search protein sequence]
KPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNR
RSKFKK
3D structure
PDB4xrs DNA-dependent formation of transcription factor pairs alters their binding specificity.
ChainI
Resolution3.5 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna I R133 K174 R181 R3 K44 R51
BS02 dna I K131 P132 R133 W176 N179 K1 P2 R3 W46 N49
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4xrs, PDBe:4xrs, PDBj:4xrs
PDBsum4xrs
PubMed26550823
UniProtO60479|DLX3_HUMAN Homeobox protein DLX-3 (Gene Name=DLX3)

[Back to BioLiP]