Structure of PDB 4w9m Chain I

Receptor sequence
>4w9mI (length=352) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]
MRPERLTVRNFLGLKNVDIEFQSGITVVEGPNGAGKSSLFEAISFALFGN
GIRYPNSYDYVNRNAVDGTARLVFQFERGGKRYEIIREINALQRKHNAKL
SEILENGKKAAIAAKPTSVKQEVEKILGIEHRTFIRTVFLPQGEIDKLLI
SPPSEITEIISDVFQSKETLEKLEKLLKEKMKKLENEIEKKLKEMSDEYN
NLDLLRKYLFDKSNFSRYFTGRVLEAVLKRTKAYLDILTNGRFDIDFDDE
KGGFIIKDWGIERPARGLSGGERALISISLAMSLAEVASGRLDAFFIDEG
FSSLDTENKEKIASVLKELERLNKVIVFITHDREFSEAFDRKLRITGGVV
VN
3D structure
PDB4w9m Structure of the Rad50 DNA double-strand break repair protein in complex with DNA.
ChainI
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna I A111 K115 S118 K182 A111 K115 S118 K182
BS02 ANP I L12 N32 G33 G35 K36 S37 S38 R53 N62 R63 Q142 L12 N32 G33 G35 K36 S37 S38 R53 N62 R63 Q142
BS03 MG I S37 Q142 S37 Q142
BS04 ANP I R762 S768 G770 E771 R263 S269 G271 E272
Gene Ontology
Molecular Function
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006302 double-strand break repair

View graph for
Molecular Function

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Biological Process
External links
PDB RCSB:4w9m, PDBe:4w9m, PDBj:4w9m
PDBsum4w9m
PubMed25349191
UniProtQ9X1X1|RAD50_THEMA DNA double-strand break repair Rad50 ATPase (Gene Name=rad50)

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