Structure of PDB 4qyz Chain I

Receptor sequence
>4qyzI (length=256) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MSNFINIHVLISHSPSCLNRDDMNMQKDAIFGGKRRVRISSQSLKRAMRK
SGYYAQNIGEQGVDIALSGRMDGAMSIAHAITTHQVDSDIDWFTAVDDLQ
EQGSAHLGTQEFSSGVFYRYANINLAQLQENLGGASREQALEIATHVVHM
LATEVPGAKQRTYAAFNPADMVMVNFSDMPLSMANAFEKAVKAKDGFLQP
SIQAFNQYWDRVANGYGLNGAAAQFSLSDVDPITAQVKQMPTLEQLKSWV
RNNGEA
3D structure
PDB4qyz Structural biology. Crystal structure of a CRISPR RNA-guided surveillance complex bound to a ssDNA target.
ChainI
Resolution3.0303 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna I N19 R20 D21 D22 K27 Q42 S43 K45 R46 R49 R165 D179 F200 T201 V203 A265 K266 N19 R20 D21 D22 K27 Q42 S43 K45 R46 R49 R70 D72 F93 T94 V96 A158 K159
BS02 dna I Q209 S211 H213 L214 Q102 S104 H106 L107
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0071667 DNA/RNA hybrid binding
Biological Process
GO:0051607 defense response to virus
GO:0099048 CRISPR-cas system
Cellular Component
GO:0032991 protein-containing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4qyz, PDBe:4qyz, PDBj:4qyz
PDBsum4qyz
PubMed25123481
UniProtQ46899|CASC_ECOLI CRISPR system Cascade subunit CasC (Gene Name=casC)

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