Structure of PDB 4qiw Chain I

Receptor sequence
>4qiwI (length=862) Species: 69014 (Thermococcus kodakarensis KOD1) [Search protein sequence]
KVIGSIEFGILSPQEIRKMSAAEITVPDTYDDDGYPIEGGLMDKRLGVID
PGLRCETCGARAGECPGHFGHIELARPVIHVGFAKTIHRVLESTCRECGR
IKLTDEEIEEYMQKFEVMGDRKGAVDKLIKEIHKKAKERMVCPHCGAPQF
PIKFERPTIYWELRKDEEGNEYKHRMMPSEVRDRLEKIPDKDLPLLGLHP
EKSRPEWMVLTVLPVPPVTMRPSITLRAEDDLTHKLVDIIRINNRLKSNI
EAGAPQLIIEDLWDLLQYHVTTYINNETSGVPPAKHKSGRPLKTLAQRLK
GFSARTVISPDPMISINEVGVPLAVAMELTVPEKVTEFNYEKLKQRVLNG
PEKYPGANYVIDPEGRRIRLMESNRELIAEKLDIGWTVERHLEDGDVVLF
NRQPSLHRMSIMAHRVRVMPYRTFRLNLPVCPPYNADFDGDEMNLHVPQT
EEAQAEAKILMEVQNHIISPRYGGPLIAGIQDHISGGYLLTREGAYFTRY
EVEQMLMFAGMDVNELPEPDKYENGEPLWSGKTIFSLLLPDDLTIWYRNK
LCDEPERCEALEKLIRKLAYDGFVYIQNGKLLSGAVDKKAYGREDGKLLD
IIVREYGVERARQFLDQVTKLTIWVITHKGFTTAIDDEDLPQEAIDRIHE
IIREAEEKVQRLIEAYKRGELEPLPGKTLEETLESKIMAVLAEARDNAGK
VAERYLGMNNHAVIMAKTGARGKILNITQMAAMLGQQSIRGKRLYRGYRG
RVLTHFKPGDLGARARGFVTNSYKSGLTPQEYFFHAMGGREGLVDTAVRT
AQSGYMQRRLINALQDLKVDYDGTVRDPTGIIVQFKYGEDGVDPMKSWQG
KTVDVDRVIVRT
3D structure
PDB4qiw The X-ray crystal structure of the euryarchaeal RNA polymerase in an open-clamp configuration.
ChainI
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG I D461 D463 D465 D437 D439 D441
BS02 ZN I C100 C103 C147 C150 C95 C98 C142 C145
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4qiw, PDBe:4qiw, PDBj:4qiw
PDBsum4qiw
PubMed25311937
UniProtQ5JE33

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