Structure of PDB 4guo Chain I

Receptor sequence
>4guoI (length=198) Species: 9606 (Homo sapiens) [Search protein sequence]
IPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIK
VSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHL
IRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVG
GMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQ
3D structure
PDB4guo structure of p73 DNA binding domain complex with 12 bp DNA
ChainI
Resolution3.19 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna I S261 R293 A296 R300 S147 R179 A182 R186
BS02 ZN I C194 H197 C258 C262 C80 H83 C144 C148
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4guo, PDBe:4guo, PDBj:4guo
PDBsum4guo
PubMed
UniProtO15350|P73_HUMAN Tumor protein p73 (Gene Name=TP73)

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