Structure of PDB 4a63 Chain I

Receptor sequence
>4a63I (length=205) Species: 9606 (Homo sapiens) [Search protein sequence]
VIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQI
KVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASH
LIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCV
GGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREAE
NLYFQ
3D structure
PDB4a63 Structural Basis for Aspp2 Recognition by the Tumor Suppressor P73.
ChainI
Resolution2.27 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN I C194 H197 C258 C262 C81 H84 C145 C149
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4a63, PDBe:4a63, PDBj:4a63
PDBsum4a63
PubMed22917970
UniProtO15350|P73_HUMAN Tumor protein p73 (Gene Name=TP73)

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