Structure of PDB 3us2 Chain I

Receptor sequence
>3us2I (length=193) Species: 9606 (Homo sapiens) [Search protein sequence]
SPSNTDYPGPHSFDVSFQQSSTKSATWTYSTELKKLYCQIAKTCPIQIKV
MTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLI
RVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGG
MNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDS
3D structure
PDB3us2 Pliable DNA Conformation of Response Elements Bound to Transcription Factor p63.
ChainI
Resolution4.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna I N270 R304 C306 A307 R311 N144 R178 C180 A181 R185
BS02 ZN I C205 H208 C273 C79 H82 C147
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3us2, PDBe:3us2, PDBj:3us2
PDBsum3us2
PubMed22247550
UniProtQ9H3D4|P63_HUMAN Tumor protein 63 (Gene Name=TP63)

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