Structure of PDB 3unf Chain I

Receptor sequence
>3unfI (length=204) Species: 10090 (Mus musculus) [Search protein sequence]
SIMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYI
GLAGLATDVQTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFG
PYYTEPVIAGLDPKTFKPFICSLDLIGCPMVTDDFVVSGTCSEQMYGMCE
SLWEPNMDPEHLFETISQAMLNAVDRDAVSGMGVIVHVIEKDKITTRTLK
ARMD
3D structure
PDB3unf Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity.
ChainI
Resolution2.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D24 R26 K40 G54 T140 D177 S180
Catalytic site (residue number reindexed from 1) D24 R26 K40 G54 T140 D177 S180
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 04C I D124 I126 D124 I126
Gene Ontology
Molecular Function
GO:0004175 endopeptidase activity
Biological Process
GO:0030163 protein catabolic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051603 proteolysis involved in protein catabolic process
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005839 proteasome core complex
GO:0019774 proteasome core complex, beta-subunit complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3unf, PDBe:3unf, PDBj:3unf
PDBsum3unf
PubMed22341445
UniProtQ9R1P1|PSB3_MOUSE Proteasome subunit beta type-3 (Gene Name=Psmb3)

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