Structure of PDB 3u33 Chain I

Receptor sequence
>3u33I (length=539) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
HWQTHTVFNQPIPLNNSNLYLSDGALCEAVTREGAGWDSDFLASIGQQLG
TAESLELGRLANVNPPELLRYDAQGRRLDDVRFHPAWHLLMQALCTNRVH
NLAWEEDARSGAFVARAARFMLHAQVEAGSLCPITMTFAATPLLLQMLPA
PFQDWTTPLLSDRYDSHLLPGGQKRGLLIGMGMTEKQGGSDVMSNTTRAE
RLEDGSYRLVGHKWFFSVPQSDAHLVLAQTAGGLSCFFVPRFLPDGQRNA
IRLERLKDKLGNRSNASCEVEFQDAIGWLLGLEGEGIRLILKMGGMTRFD
CALGSHAMMRRAFSLAIYHAHQRHVFGNPLIQQPLMRHVLSRMALQLEGQ
TALLFRLARAWDRRADAKEALWARLFTPAAKFVICKRGMPFVAEAMEVLG
GIGYCEESELPRLYREMPVNSIWEGSGNIMCLDVLRVLNKQAGVYDLLSE
AFVEVKGQDRYFDRAVRRLQQQLRKPAEELGREITHQLFLLGCGAQMLKY
ASPPMAQAWCQVMLDTRGGVRLSEQIQNDLLLRATGGVC
3D structure
PDB3u33 Flavin-induced oligomerization in Escherichia coli adaptive response protein AidB.
ChainI
Resolution2.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) M184 T185 T298 E425 R437
Catalytic site (residue number reindexed from 1) M183 T184 T297 E424 R436
Enzyme Commision number 1.3.99.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD I M182 M184 T185 G190 S191 F216 S218 W424 G426 S427 N429 L433 M181 M183 T184 G189 S190 F215 S217 W423 G425 S426 N428 L432
BS02 FAD I R324 F327 L331 Q334 M337 E398 V399 G402 R323 F326 L330 Q333 M336 E397 V398 G401
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003995 acyl-CoA dehydrogenase activity
GO:0005515 protein binding
GO:0008470 3-methylbutanoyl-CoA dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0042802 identical protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006974 DNA damage response
GO:0045892 negative regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:3u33, PDBe:3u33, PDBj:3u33
PDBsum3u33
PubMed22004173
UniProtP33224|AIDB_ECOLI Putative acyl-CoA dehydrogenase AidB (Gene Name=aidB)

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