Structure of PDB 3qgk Chain I

Receptor sequence
>3qgkI (length=564) Species: 679897 (Helicobacter mustelae 12198) [Search protein sequence]
MKMKRQEYVNTYGPTTGDKVRLGDTDLWAEVEHDYTVYGEELKFGAGKTI
REGMGQSNSPDENTLDLVITNALIIDYTGIYKADIGIKNGKIHGIGKAGN
KDMQDGVTPHMVVGVGTEALAGEGMIITAGGIDSHTHFLSPQQFPTALAN
GVTTMFGGGTGPVDGTNATTITPGVWNLHRMLRAAEEYGMNVGLLGKGNS
SSRAQLVEQVKAGAIGFKLHEDWGTTPSAIDHCLSVADEYDVQVCIHTDT
VNEAGYVDDTLRAMNGRAIHAYHIEGAGGGHSPDVITMAGEVNILPSSTT
PTIPYTINTVAEHLDMLMTCHHLDKRIRFSQSRIRPGSIAAEDTLHDMGV
IAMTSSDSQAMGRAGEVIPRTWQTADKNKKEFGRLTEEKGDNDNFRIKRY
ISKYTINPAITHGVSEYIGSVEEGKIADLVVWNPAFFGVKPKIIIKGGMV
VFSEMGDSNASVPTPQPVYYREMFGHHGKAKFDTSITFVSKVAYENGIKE
KLGLERKVLPVKNCRNVTKKDFKFNNTTAKITVNPETFEVFVNGKLCTSK
PATEVALASRYTFF
3D structure
PDB3qgk Iron-containing urease in a pathogenic bacterium.
ChainI
Resolution3.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H135 H137 K218 H220 D222
Catalytic site (residue number reindexed from 1) H135 H137 K218 H220 D222
Enzyme Commision number 3.5.1.5: urease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE I K218 H220 H247 H273 K218 H220 H247 H273
BS02 FE I H135 H137 K218 D361 H135 H137 K218 D357
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0009039 urease activity
GO:0016151 nickel cation binding
GO:0016787 hydrolase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0046872 metal ion binding
Biological Process
GO:0043419 urea catabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3qgk, PDBe:3qgk, PDBj:3qgk
PDBsum3qgk
PubMed21788478
UniProtD3UJ80

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