Structure of PDB 3kxf Chain I

Receptor sequence
>3kxfI (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRTEPRAP
WIEQEGPEYWDRNTAIFKANTQTYRESLRNLRGYYNQSEAGSHIIQRMYG
CDLGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEARRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPVSDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB3kxf Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability
ChainI
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide I Y7 N63 I66 F67 A69 T73 Y74 E76 S77 Y84 R97 Y99 S116 K146 W147 V152 A155 R156 Y159 W167 Y171 Y7 N63 I66 F67 A69 T73 Y74 E76 S77 Y84 R97 Y99 S116 K146 W147 V152 A155 R156 Y159 W167 Y171
External links
PDB RCSB:3kxf, PDBe:3kxf, PDBj:3kxf
PDBsum3kxf
PubMed20483993
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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