Structure of PDB 3a5c Chain I

Receptor sequence
>3a5cI (length=561) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MIQGVIQKIAGPAVIAKGMLGARMYDICKVGEEGLVGEIIRLDGDTAFVQ
VYEDTSGLKVGEPVVSTGLPLAVELGPGMLNGIYDGIQRPLVHALDREKK
WAWTPMVKPGDEVRGGMVLGTVPEFGFTHKILVPPDVRGRVKEVKPAGEY
TVEEPVVVLEDGTELKMYHTWPVRRARPVQRKLDPNTPFLTGMRILDVLF
PVAMGGTAAIPGPFGSGKTVTQQSLAKWSNADVVVYVGCGERGNEMTDVL
VEFPELTDPKTGGPLMHRTVLIANTSNMPVAAREASIYVGVTIAEYFRDQ
GFSVALMADSTSRWAEALREISSRLEEMPAEEGYPPYLAARLAAFYERAG
KVITLGGEEGAVTIVGAVSPPGGDMSEPVTQSTLRIVGAFWRLDASLAFR
RHFPAINWNGSYSLFTSALDPWYRENVAEDYPELRDAISELLQREAGLQE
IVQLVGPDALQDAERLVIEVGRIIREDFLQQNAYHEVDAYCSMKKAYGIM
KMILAFYKEAEAAIKRGVSIDEILQLPVLERIGRARYVSEEEFPAYFEEA
MKEIQGAFKAL
3D structure
PDB3a5c Inter-subunit interaction and quaternary rearrangement defined by the central stalk of prokaryotic V1-ATPase
ChainI
Resolution4.51 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K234 E257 R258 L430
Catalytic site (residue number reindexed from 1) K218 E241 R242 L414
Enzyme Commision number 7.1.2.2: H(+)-transporting two-sector ATPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP I G231 G233 K234 T235 V236 G215 G217 K218 T219 V220
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism
GO:0046961 proton-transporting ATPase activity, rotational mechanism
Biological Process
GO:0006754 ATP biosynthetic process
GO:0042777 proton motive force-driven plasma membrane ATP synthesis
GO:0046034 ATP metabolic process
GO:1902600 proton transmembrane transport
Cellular Component
GO:0045259 proton-transporting ATP synthase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3a5c, PDBe:3a5c, PDBj:3a5c
PDBsum3a5c
PubMed19779483
UniProtQ56403|VATA_THET8 V-type ATP synthase alpha chain (Gene Name=atpA)

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