Structure of PDB 2y9h Chain I

Receptor sequence
>2y9hI (length=195) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
GAMWLTKLVLNPASRAARRDLANPYEMHRTLSKAVSRALEEGRERLLWRL
EPAEPPVVLVQTLTEPDWSVLDGYAQVFPPKPFHPALKPGQRLRFRLRAN
PAKRLAATGKRVALKTPAEKVAWLERRLEEGGFRLLERGPWVQILQDTFL
ELLQVQAVLFEGRLEVVDPERALATLRRGVGPGKALGLGLLSVAP
3D structure
PDB2y9h An RNA-Induced Conformational Change Required for Crispr RNA Cleavage by the Endoribonuclease Cse3.
ChainI
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna I R13 R16 R15 R18
BS02 rna I Y23 R43 K105 R106 L107 A108 K112 R113 R128 R129 L169 Q170 K200 L202 Y25 R45 K103 R104 L105 A106 K110 R111 R126 R127 L153 Q154 K184 L186
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0051607 defense response to virus

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2y9h, PDBe:2y9h, PDBj:2y9h
PDBsum2y9h
PubMed21572442
UniProtQ53WG9|CAS6_THET8 CRISPR-associated endoribonuclease Cse3 (Gene Name=cse3)

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