Structure of PDB 2x4y Chain I

Receptor sequence
>2x4yI (length=125) Species: 9606 (Homo sapiens) [Search protein sequence]
DSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLK
LGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEG
RKSNIRKSVQIAYHRALQHRSKVQG
3D structure
PDB2x4y Molecular Basis of Histone H3K36Me3 Recognition by the Pwwp Domain of Brpf1.
ChainI
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide I Y1096 Y1099 P1119 P1121 L1130 F1147 K1151 R1152 T1153 W1154 Q1155 Y17 Y20 P40 P42 L51 F68 K72 R73 T74 W75 Q76
External links
PDB RCSB:2x4y, PDBe:2x4y, PDBj:2x4y
PDBsum2x4y
PubMed20400950
UniProtP55201|BRPF1_HUMAN Peregrin (Gene Name=BRPF1)

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