Structure of PDB 2hpc Chain I

Receptor sequence
>2hpcI (length=305) Species: 9606 (Homo sapiens) [Search protein sequence]
EIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKD
TVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGW
TVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSA
IPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFD
GFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHA
GHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNR
LTIGE
3D structure
PDB2hpc ?
ChainI
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide I F295 D297 D301 T305 D330 K338 C339 H340 Y363 D364 F204 D206 D210 T214 D239 K247 C248 H249 Y272 D273
BS02 CA I D320 F322 G324 D229 F231 G233
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2hpc, PDBe:2hpc, PDBj:2hpc
PDBsum2hpc
PubMed
UniProtP02679|FIBG_HUMAN Fibrinogen gamma chain (Gene Name=FGG)

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