Structure of PDB 2gxa Chain I

Receptor sequence
>2gxaI (length=270) [Search protein sequence]
TEKFDFGTMVQWAYDHKYAEESKIAYEYALAAGSDSNARAFLATNSQAKH
VKDCATMVRHYLRAETQALSMPAYIKARCKLATGEGSWKSILTFFNYQNI
ELITFINALKLWLKGIPKKNCLAFIGPPNTGKSMLCNSLIHFLGGSVLSF
ANHKSHFWLASLADTRAALVDDATHACWRYFDTYLRNALDGYPVSIDRKH
KAAVQIKAPPLLVTSNIDVQAEDRYLYLHSRVQTFRFEQPCTDESGEQPF
NITDADWKSFFVRLWGRLDL
3D structure
PDB2gxa Mechanism of DNA translocation in a replicative hexameric helicase.
ChainI
Resolution3.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna I F464 K506 H507 F157 K199 H200
BS02 ADP I P424 K425 Y499 P117 K118 Y192
BS03 ADP I N436 T437 G438 K439 S440 M441 Q555 F557 N558 N129 T130 G131 K132 S133 M134 Q248 F250 N251
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0005524 ATP binding
Biological Process
GO:0006260 DNA replication

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2gxa, PDBe:2gxa, PDBj:2gxa
PDBsum2gxa
PubMed16855583
UniProtP03116|VE1_BPV1 Replication protein E1 (Gene Name=E1)

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