Structure of PDB 2fx9 Chain I

Receptor sequence

>2fx9I (length=227) Species: 9606 (Homo sapiens) [Search protein sequence]

QVQLVQSGAEVKRPGSSVTVSCKASGGSFSTYALSWVRQAPGRGLEWMGG
VIPLLTITNYAPRFQGRITITADRSTSTAYLELNSLRPEDTAVYYCAREG
TTGWGWLGKPIGAFAHWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTA
ALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPS
SSLGTQTYICNVNHKPSNTKVDKKVEP

3D structure

PDB

2fx9 Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.

Chain

Resolution

2.1 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	I	T31 A33 G50 V51 I52 I56 N58 E95 K100E P100F	T31 A33 G50 V51 I52 I57 N59 E99 K109 P110

External links

PDB	RCSB:2fx9, PDBe:2fx9, PDBj:2fx9
PDBsum	2fx9
PubMed	17125793

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