Structure of PDB 2c38 Chain I

Receptor sequence
>2c38I (length=271) Species: 2287 (Saccharolobus solfataricus) [Search protein sequence]
MSSTPSNQNIIPIIKKESIVSLFEKGIRQDGRKLTDYRPLSITLDYAKKA
DGSALVKLGTTMVLAGTKLEIDKPYEDTPNQGNLIVNVELLPLAYETFEP
GPPDENAIELARVVDRSLRDSKALDLTKLVIEPGKSVWTVWLDVYVLDYG
GNVLDACTLASVAALYNTKVYKVEQISVNKNEVVGKLPLNYPVVTISVAK
VDKYLVVDPDLDEESIMDAKISFSYTPDLKIVGIQKSGKGSMSLQDIDQA
ENTARSTAVKLLEELKKHLGI
3D structure
PDB2c38 Structural Basis of 3' End RNA Recognition and Exoribonucleolytic Cleavage by an Exosome Rnase Ph Core.
ChainI
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.13.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP I R112 D115 R112 D115
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0035925 mRNA 3'-UTR AU-rich region binding
Biological Process
GO:0006401 RNA catabolic process
GO:0016075 rRNA catabolic process
Cellular Component
GO:0000177 cytoplasmic exosome (RNase complex)
GO:0000178 exosome (RNase complex)
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2c38, PDBe:2c38, PDBj:2c38
PDBsum2c38
PubMed16285928
UniProtQ9UXC0|RRP42_SACS2 Exosome complex component Rrp42 (Gene Name=rrp42)

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