Structure of PDB 1ml1 Chain I

Receptor sequence
>1ml1I (length=241) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]
SKPQPIAAANWKSGSPDSLSELIDLFNSTSINHDVQCVVASTFVHLAMTK
ERLSHPKFVIAAQNAGNADALASLKDFGVNWIVLGHSERRWYYGETNEIV
ADKVAAAVASGFMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADW
AKVVIAYEPVWAIGTGKVATPQQAQEAHALIRSWVSSKIGADVAGELRIL
YGGSVNGKNARTLYQQRDVNGFLVGGASLKPEFVDIIKATQ
3D structure
PDB1ml1 Protein engineering with monomeric triosephosphate isomerase (monoTIM): the modelling and structure verification of a seven-residue loop.
ChainI
Resolution2.6 Å
3D
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Enzymatic activity
Enzyme Commision number 5.3.1.1: triose-phosphate isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PGA I N11 K13 H95 E167 I172 G173 G234 G235 N10 K12 H86 E158 I163 G164 G225 G226
Gene Ontology
Molecular Function
GO:0004807 triose-phosphate isomerase activity
GO:0016853 isomerase activity
Biological Process
GO:0006094 gluconeogenesis
GO:0006096 glycolytic process
GO:0019563 glycerol catabolic process
GO:0046166 glyceraldehyde-3-phosphate biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0020015 glycosome

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Cellular Component
External links
PDB RCSB:1ml1, PDBe:1ml1, PDBj:1ml1
PDBsum1ml1
PubMed9089815
UniProtP04789|TPIS_TRYBB Triosephosphate isomerase, glycosomal

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