Structure of PDB 1de4 Chain I

Receptor sequence
>1de4I (length=635) Species: 9606 (Homo sapiens) [Search protein sequence]
LYWDDLKRKLSEKLDSTDFTSTIKLLNENSYVPREAGSQKDENLALYVEN
QFREFKLSKVWRDQHFVKIQVKDSAQNSVIIVDKNGRLVYLVENPGGYVA
YSKAATVTGKLVHANFGTKKDFEDLYTPVNGSIVIVRAGKITFAEKVANA
ESLNAIGVLIYMDQTKFPIVNAELSFFGHAHLGTGDPYTPGFPSFNHTQF
PPSRSSGLPNIPVQTISRAAAEKLFGNMEGDCPSDWKTDSTCRMVTSESK
NVKLTVSNVLKEIKILNIFGVIKGFVEPDHYVVVGAQRDAWGPGAAKSGV
GTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSAGDFGSVGATEWLEGYL
SSLHLKAFTYINLDKAVLGTSNFKVSASPLLYTLIEKTMQNVKHPVTGQF
LYQDSNWASKVEKLTLDNAAFPFLAYSGIPAVSFCFCEDTDYPYLGTTMD
TYKELIERIPELNKVARAAAEVAGQFVIKLTHDVELNLDYERYNSQLLSF
VRDLNQYRADIKEMGLSLQWLYSARGDFFRATSRLTTDFGNAEKTDRFVM
KKLNDRVMRVEYHFLSPYVSPKESPFRHVFWGSGSHTLPALLENLKLRKQ
NNGAFNETLFRNQLALATWTIQGAANALSGDVWDI
3D structure
PDB1de4 Crystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptor.
ChainI
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA I T310 F313 E465 E468 T189 F192 E344 E347
Gene Ontology
Molecular Function
GO:0004998 transferrin receptor activity
Biological Process
GO:0033572 transferrin transport

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Molecular Function
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Biological Process
External links
PDB RCSB:1de4, PDBe:1de4, PDBj:1de4
PDBsum1de4
PubMed10638746
UniProtP02786|TFR1_HUMAN Transferrin receptor protein 1 (Gene Name=TFRC)

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