Structure of PDB 8z9h Chain H

Receptor sequence
>8z9hH (length=449) Species: 126796 (Thogoto virus (isolate SiAr 126)) [Search protein sequence]
SVGTTFRTLLKRDTDWDVIPTPRVEPNVPRIEGRRWTQMKKLPLLKEKEG
PPSPWRALLLGADSEYIVCPPGTDQEAISWIHSQSEIECIRESKSTPASV
ITCLTSSLQSFAEGNPVRSRIHEDIIAFGINKKQEKKQSASSSASGEWKR
AEYQVEEMSLPPWVEEEMVLLRSDQEDNWIELEKNAIYTEVDGVAEGLVD
KYIEIVGRTKVASVIEKWQIAATRTFSQLHTDRSRITACPIITRDPSGNC
QFWGMVLLGPHHVKRDTDNAPLLIAEIMGEDTEEKYPKHSVFSLKVEEKQ
FLLSLKITSFSRNKLYTFSNIRRVLIQPASIYSQVVLSRAAENNSLNLEV
NPEIQLYLEGAQRGMTLYQWVRMILCLEFLMAIYNNPQMEGFLANMRRLH
MSRHAMMERRQVFLPFGSRPEDKVNECIINNPIVAYLAKGWNSMPNVYY
3D structure
PDB8z9h Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses
ChainH
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna H S268 G302 K306 K309 Y326 N442 K461 K479 I480 T481 S482 F483 S95 G129 K133 K136 Y153 N269 K288 K306 I307 T308 S309 F310
BS02 V9G H S268 G302 K305 K309 S95 G129 K132 K136
Gene Ontology
Cellular Component
GO:0042025 host cell nucleus
GO:0044423 virion component

View graph for
Cellular Component
External links
PDB RCSB:8z9h, PDBe:8z9h, PDBj:8z9h
PDBsum8z9h
PubMed38816392
UniProtP27194|PA_THOGV Polymerase acidic protein (Gene Name=Segment)

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