Structure of PDB 8z9e Chain H

Receptor sequence

>8z9eH (length=553) Species: 256318 (metagenome) [Search protein sequence]

MIKFIGGASKVTGSAFLLETGNAKILIDCGIEQEKDNNEIIEKKINEIGK
ADICILTHAHLAASGLVPLLVKKRKVNKIISTPATKELCRLLFNDFQRIQ
EENNDIPLYSYDDIESSFEIWDEIDDRNTIELFDTKITFYNNSHIIGSVS
VFIETHNGNYLFSGDIGSKLQQLMDYPPDMPDGNVDYLILESTYRDRLLE
IAKTTCENVLIPSFAIGRLQEVLYTFSNYNFNFPVYIDSPMGSKVTNLIK
EYNIYLKKKLRRDLFNNKYIAINTSNQSKELSNSKEPAVIISASGMLEGG
RILNHLEQIKNDENSTLIFVGYQAQNTRGRKILDGERIEKLNSFSAHADQ
DELIDYIERLKYTPYKVFLVHGEKEQREILAKRIISKKIRVELPENYEIL
IEKKVVLNINTDNMCNFASYRLMPFSGFIVEKDRIEINDKNWFDMIWALP
DMSHDKIIENIEYLFNIKILSKNRIKEFWEEFCKGQKAAIKYITQVHRKN
PNTGRRNWNPPEGDFTDNEIEKLYETAYNTLLSLIKYDKNKVYNILINFN
PKL

3D structure

PDB

8z9e Structural basis for the activity of the type VII CRISPR-Cas system.

Chain

Resolution

3.13 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	H	Q33 E34 H64 L65 L96 D99 F100 R102 I103 Y198 F230 A231 R234 P256 N294 N297 A314 S315 G316 M317 E319 G320 G321 R322 Y343 A345 F370 S371 S527 K528 N529 R530 N556 N558 N565 K608	Q33 E34 H60 L61 L92 D95 F96 R98 I99 Y194 F214 A215 R218 P240 N273 N276 A293 S294 G295 M296 E298 G299 G300 R301 Y322 A324 F344 S345 S471 K472 N473 R474 N500 N502 N509 K552
BS02	ZN	H	H62 H64 H148 D169	H58 H60 H144 D165

External links

PDB	RCSB:8z9e, PDBe:8z9e, PDBj:8z9e
PDBsum	8z9e
PubMed	39143216

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