Structure of PDB 8z9c Chain H

Receptor sequence

>8z9cH (length=565) Species: 256318 (metagenome) [Search protein sequence]

MIKFIGGASKVTGSAFLLETGNAKILIDCGIEQENNEIIEKKINEIGKAD
ICILTHAHLAASGLVPLLVKKRKVNKIISTPATKELCRLLFNDFQRIQEE
NNDIPLYSYDDIESSFEIWDEIDDRNTIELFDTKITFYNNSHIIGSVSVF
IETHNGNYLFSGDIGSKLQQLMDYPPDMPDGNVDYLILESTYSDRDRLLE
IAKTTCENGGKVLIPSFAIGRLQEVLYTFSNYNFNFPVYIDSPMGSKVTN
LIKEYNIYLKKKLRRDDLFNNKYIAINTSNQSKELSNSKEPAVIISASGM
LEGGRILNHLEQIKNDENSTLIFVGYQAQNTRGRKILDGEEKVRCRIEKL
NSFSAHADQDELIDYIERLKYTPYKVFLVHGEKEQREILAKRIISKKIRV
ELPENEILIEKKVVLNINTDNMCNFASYRLMPFSGFIVEKDDRIEINDKN
WFDMIWNEEALPDMSHDKIIENIEYLFNIKILSKNRIKEFWEEFCKGQKA
AIKYITQVHRKNPNTGRRNWNPPEGDFTDNEIEKLYETAYNTLLSLIKYD
KNKVYNILINFNPKL

3D structure

PDB

8z9c Structural basis for the activity of the type VII CRISPR-Cas system.

Chain

Resolution

3.01 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	H	Q33 E34 H64 L96 D99 F100 I103 Y198 F230 A231 I232 R234 P256 M257 Q298 A314 S315 M317 E319 G320 G321 R322 L324 G342 Y343 H373 S527 K528 N529 R530 N556 N558 T559 N563 N565 K608	Q33 E34 H58 L90 D93 F94 I97 Y192 F217 A218 I219 R221 P243 M244 Q281 A297 S298 M300 E302 G303 G304 R305 L307 G325 Y326 H356 S483 K484 N485 R486 N512 N514 T515 N519 N521 K564
BS02	ZN	H	H62 H64 H148 D169	H56 H58 H142 D163

External links

PDB	RCSB:8z9c, PDBe:8z9c, PDBj:8z9c
PDBsum	8z9c
PubMed	39143216

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