Structure of PDB 8xfy Chain H

Receptor sequence
>8xfyH (length=277) Species: 9606 (Homo sapiens) [Search protein sequence]
GHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLK
VRRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK
EVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTD
FGLSKEFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGK
DRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEI
KRHSFFSTIDWNKLYRREIHPPFKPAT
3D structure
PDB8xfy The Crystal Structure of RSK2 from Biortus.
ChainH
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1LU8 H K100 V131 D148 F149 L150 L200 T210 D211 F212 K42 V70 D87 F88 L89 L139 T149 D150 F151
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:8xfy, PDBe:8xfy, PDBj:8xfy
PDBsum8xfy
PubMed
UniProtP51812|KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 (Gene Name=RPS6KA3)

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