Structure of PDB 8wte Chain H

Receptor sequence

>8wteH (length=274) Species: 9606 (Homo sapiens) [Search protein sequence]

GSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEDGSHTIQIMYG
CDVGPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAA
HAAEQQRAYLEGRCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRW

3D structure

PDB

8wte Identification and affinity enhancement of T-cell receptor targeting a KRASG12V cancer neoantigen

Chain

Resolution

2.17 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	H	Y7 Y9 E63 D77 Y84 Y99 R114 D116 T143 K146 W147 A150 Q156 Y159 R163 W167 Y171	Y7 Y9 E63 D77 Y84 Y99 R114 D116 T143 K146 W147 A150 Q156 Y159 R163 W167 Y171

External links

PDB	RCSB:8wte, PDBe:8wte, PDBj:8wte
PDBsum	8wte
PubMed	38684865
UniProt	A0A583ZB34

[Back to BioLiP]