Structure of PDB 8w7e Chain H

Receptor sequence
>8w7eH (length=175) Species: 9606 (Homo sapiens) [Search protein sequence]
LIPIVVERAYDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKK
PIHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGT
PGMRHSLPNSRIMIHQPSAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESA
MERDRYMSPMEAQEFGILDKVLVHP
3D structure
PDB8w7e Design, synthesis and biological evaluations of novel small molecular hyper-activators of human caseinolytic peptidase P (hClpP)
ChainH
Resolution2.8 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 9I3 H L104 F105 S108 T135 Y138 L41 F42 S45 T72 Y75
BS02 9I3 H L79 E82 I84 H116 Y118 W146 V148 L170 L16 E19 I21 H53 Y55 W83 V85 L107
External links
PDB RCSB:8w7e, PDBe:8w7e, PDBj:8w7e
PDBsum8w7e
PubMed
UniProtQ16740|CLPP_HUMAN ATP-dependent Clp protease proteolytic subunit, mitochondrial (Gene Name=CLPP)

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