Structure of PDB 8r5h Chain H

Receptor sequence
>8r5hH (length=149) Species: 9606 (Homo sapiens) [Search protein sequence]
PVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIH
SYRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKE
RCLQVVRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQERIAHQ
3D structure
PDB8r5h Cullin-RING ligases target substrates with geometrically optimized catalytic partners
ChainH
Resolution3.44 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 759 H W88 Y98 P99 R107 I109 H110 Y112 H115 W117 W28 Y38 P39 R47 I49 H50 Y52 H55 W57
External links
PDB RCSB:8r5h, PDBe:8r5h, PDBj:8r5h
PDBsum8r5h
PubMed38382526
UniProtP40337|VHL_HUMAN von Hippel-Lindau disease tumor suppressor (Gene Name=VHL)

[Back to BioLiP]