Structure of PDB 8pn9 Chain H

Receptor sequence
>8pn9H (length=112) Species: 9606 (Homo sapiens) [Search protein sequence]
PSAMTVYALVVVSYFLITGGIIYDVIVEPPSVGSRPVAFLAYRVNGQYIM
EGLASSFLFTMGGLGFIILDRSNAPNIPKLNRFLLLFIGFVCVLLSFFMA
RVFMRMKLPGYL
3D structure
PDB8pn9 Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-kappa B.
ChainH
Resolution3.61 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 KZB H I49 V52 I22 V25
BS02 EGY H A30 L36 S40 A3 L9 S13
Gene Ontology
Molecular Function
GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity
GO:0005515 protein binding
Biological Process
GO:0006486 protein glycosylation
GO:0006487 protein N-linked glycosylation
GO:0018279 protein N-linked glycosylation via asparagine
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0008250 oligosaccharyltransferase complex
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:8pn9, PDBe:8pn9, PDBj:8pn9
PDBsum8pn9
PubMed38670073
UniProtQ9NRP0|OSTC_HUMAN Oligosaccharyltransferase complex subunit OSTC (Gene Name=OSTC)

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