Structure of PDB 8p0j Chain H

Receptor sequence

>8p0jH (length=382) Species: 10245 (Vaccinia virus) [Search protein sequence]

MDNLFTFLHEIEDRYARTIFNFHLISCDEIGDIYGLMKERISSEDMFDNI
VYNKDIHPAIKKLVYCDIQLTKHIINQNTYPVFNDSSQVKCCHYFDINSD
NSNISSRTVEIFEREKSSLVSYIKTTNKKRKVNYGEIKKTVHGGTNANYF
SGKKSDEYLSTTVRSNINQPWIKTISKRMRVDIINHSIVTRGKSSILQTI
EIIFTNRTCVKIFKDSTMHIILSKDKDEKGCIHMIDKLFYVYYNLFLLFE
DIIQNEYFKEVANVVNHVLTATALDEKLFLIKKMAEHDVYGVSNFKIGMF
NLTFIKSLDHTVFPSLLDEDSKIKFFKGKKLNIVALRSLEDCINYVTKSE
NMIEMMKERSTILNSIDIETESVDRLKELLLK

3D structure

PDB

8p0j Cryo EM map and model of the vaccinia RNA polymerase intermediate pre-initiation open promoter complex (CASP target)

Chain

Resolution

2.39 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	H	H23 K116 K128 Y134 G135 I196 Q198 F213 D215 H219 M299 K324 F326 V334	H23 K116 K128 Y134 G135 I196 Q198 F213 D215 H219 M299 K324 F326 V334
BS02	dna	H	T18 I19 N21 S121 Y122 T125 K129 K193 S195 I196 R207 K211 I221 S223 K224 K327	T18 I19 N21 S121 Y122 T125 K129 K193 S195 I196 R207 K211 I221 S223 K224 K327

External links

PDB	RCSB:8p0j, PDBe:8p0j, PDBj:8p0j
PDBsum	8p0j
PubMed
UniProt	P20998\|VITF3_VACCC Intermediate transcription factor 3 large subunit (Gene Name=OPG150)

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