Structure of PDB 8oeq Chain H

Receptor sequence

>8oeqH (length=206) Species: 5476 (Candida albicans) [Search protein sequence]

LQVVELATTIPLDVQEAQREVKLFNKWSFEDVEVKDVSLVDYIQIRNPVF
VSHTAGKYASKRFRKAQCPIVERLTNSLMMNGRNNGKKLKAVRIVKHALE
IIHVLTEQNPIQVVVDAIVNSGAREDSTRIGSSGTVRRQAVDVSPLRRVN
QAIALLTIGAREASFRNIKTIAECLAEELINAAKGSSTSYAIKKKDELER
VAKSNR

3D structure

PDB

8oeq Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement

Chain

Resolution

3.3 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	H	H72 A78 K80 R81 K84 R92 N95 L97 M98 N100 G101 R102 N103 N104 G105 K106 K107 L108 K109 S152 R166 N169 R180 S183 F184 R185 I187 T189 I190	H53 A59 K61 R62 K65 R73 N76 L78 M79 N81 G82 R83 N84 N85 G86 K87 K88 L89 K90 S133 R147 N150 R161 S164 F165 R166 I168 T170 I171
BS02	MG	H	S183 N186 K188	S164 N167 K169

External links

PDB	RCSB:8oeq, PDBe:8oeq, PDBj:8oeq
PDBsum	8oeq
PubMed
UniProt	A0A8H6BS29

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