Structure of PDB 8jko Chain H

Receptor sequence
>8jkoH (length=104) Species: 9606 (Homo sapiens) [Search protein sequence]
GKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQDDAALFKAWAL
FKGKFREGIDKPDPPTWKRRLRCALNKSNDFEELVERSQLDISDPYKVYR
IVPE
3D structure
PDB8jko Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
ChainH
Resolution2.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna H W54 H56 A57 K59 K94 R95 R98 K103 W33 H35 A36 K38 K68 R69 R72 K77
BS02 dna H G22 K23 L24 H56 W74 R96 A100 K103 G1 K2 L3 H35 W48 R70 A74 K77
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8jko, PDBe:8jko, PDBj:8jko
PDBsum8jko
PubMed37683642
UniProtF2Z3D5

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