Structure of PDB 8jkn Chain H

Receptor sequence
>8jknH (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
GKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQDYNREEDAALF
KAWALFKGKFREGIDKPDPPTWKRRLRCALNKSNDFEELVERSQLDISDP
YKVYRIVPE
3D structure
PDB8jkn Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
ChainH
Resolution2.92 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna H W54 H56 A57 K59 K94 R98 K103 W33 H35 A36 K38 K73 R77 K82
BS02 dna H K23 H56 K59 R64 W74 K78 K80 R96 K103 K2 H35 K38 R43 W53 K57 K59 R75 K82
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8jkn, PDBe:8jkn, PDBj:8jkn
PDBsum8jkn
PubMed37683642
UniProtF2Z3D5

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