Structure of PDB 8iaj Chain H

Receptor sequence
>8iajH (length=182) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
STPVTDHRRRRAAAVISHVEQETFEDENDQQMLPNMNATWVDQRGAWLIH
IVVIVLLRLFYSLFGSTPKWTWTLTNMTYIIGFYIMFHLVKGTPFDFNGG
AYDNLTMWEQINDETLYTPTRKFLLIVPIVLFLISNQYYRNDMTLFLSNL
AVTVLIGVVPKLGITHRLRISIPGITGRAQIS
3D structure
PDB8iaj Collaborative regulation of yeast SPT-Orm2 complex by phosphorylation and ceramide.
ChainH
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 Z1T H N71 W74 H84 M120 N37 W40 H50 M86
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0006672 ceramide metabolic process
GO:0006986 response to unfolded protein
GO:0030148 sphingolipid biosynthetic process
GO:0090155 negative regulation of sphingolipid biosynthetic process
GO:0090156 intracellular sphingolipid homeostasis
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0017059 serine palmitoyltransferase complex

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Biological Process
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Cellular Component
External links
PDB RCSB:8iaj, PDBe:8iaj, PDBj:8iaj
PDBsum8iaj
PubMed38285738
UniProtQ06144|ORM2_YEAST Protein ORM2 (Gene Name=ORM2)

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