Structure of PDB 8hkj Chain H

Receptor sequence
>8hkjH (length=415) Species: 1396 (Bacillus cereus) [Search protein sequence]
IPQPKTYGPLGNLPLIDKDKPTLSFIKIAEEYGPIFQIQTLSDTIIVVSG
HELVAEVCDETRFDKSIEGALAKVRAFAGDGLFTSETHEPNWKKAHNILM
PTFSQRAMKDYHAMMVDIAVQLVQKWARLNPNENVDVPEDMTRLTLDTIG
LCGFNYRFNSFYRETPHPFITSMTRALDIQSMFSLVDNIIAERNDLLSRM
LNVPDPETGEKLDDENIRFQIITFLIAGHETTSGLLSFAIYFLLKNPDKL
KKAYEEVDRVLTDPTPTYQQVMKLKYMRMILNESLRLWPTAPAFSLYAKE
DTVIGGKYPIKKGEDRISVLIPQLHRDKDAWGDNVEEFQPERFEELDKVP
HHAYKPFGNGQRACIGMQFALHEATLVMGMLLQHFELIDYQNYQLDVKQT
LTLKPGDFKIRILPR
3D structure
PDB8hkj Investigating the applicability of the CYP102A1-decoy-molecule system to other members of the CYP102A subfamily.
ChainH
Resolution2.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.14.14.1: unspecific monooxygenase.
1.6.2.4: NADPH--hemoprotein reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM H K72 L89 F90 W99 A268 G269 T272 T273 L276 A332 F335 P397 F398 G399 R403 C405 I406 G407 A411 K65 L82 F83 W92 A227 G228 T231 T232 L235 A291 F294 P356 F357 G358 R362 C364 I365 G366 A370
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding

View graph for
Molecular Function
External links
PDB RCSB:8hkj, PDBe:8hkj, PDBj:8hkj
PDBsum8hkj
PubMed37167731
UniProtQ81BF4|C102_BACCR Bifunctional cytochrome P450/NADPH--P450 reductase (Gene Name=CYP102A5)

[Back to BioLiP]