Structure of PDB 8h6d Chain H

Receptor sequence
>8h6dH (length=163) Species: 9606 (Homo sapiens) [Search protein sequence]
GIIEFHVIGNSLTNRRVLLWLVGLQNVFSHQLPRMPKEYIARLVFDPKHK
TLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLK
EYHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGAT
LMECELNPRIPYT
3D structure
PDB8h6d Molecular Basis of KAT2A Selecting Acyl-CoA Cofactors for Histone Modifications.
ChainH
Resolution3.26 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GRA H L531 M534 V577 C579 A580 V581 Q586 V587 G589 Y590 G591 T592 Y613 Y617 A618 G620 Y621 K624 L32 M35 V78 C80 A81 V82 Q87 V88 G90 Y91 G92 T93 Y114 Y118 A119 G121 Y122 K125
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups

View graph for
Molecular Function
External links
PDB RCSB:8h6d, PDBe:8h6d, PDBj:8h6d
PDBsum8h6d
PubMed37040526
UniProtQ92830|KAT2A_HUMAN Histone acetyltransferase KAT2A (Gene Name=KAT2A)

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