Structure of PDB 8fvw Chain H

Receptor sequence

>8fvwH (length=73) Species: 83333 (Escherichia coli K-12) [Search protein sequence]

ARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIAL
REIEEGLINNQILDVRERQEQQE

3D structure

PDB

8fvw Control of transcription elongation and DNA repair by alarmone ppGpp.

Chain

Resolution

2.1 Å

3D
structure

Enzymatic activity

Enzyme Commision number

2.7.7.6: DNA-directed RNA polymerase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	G4P	H	A2 R3 V4 T5	A1 R2 V3 T4

Gene Ontology

	Molecular Function
GO:0001000	bacterial-type RNA polymerase core enzyme binding
GO:0003677	DNA binding
GO:0003899	DNA-directed 5'-3' RNA polymerase activity
GO:0016779	nucleotidyltransferase activity
GO:0034062	5'-3' RNA polymerase activity

	Biological Process
GO:0006351	DNA-templated transcription
GO:0006352	DNA-templated transcription initiation
GO:0006879	intracellular iron ion homeostasis
GO:0009408	response to heat
GO:0031564	transcription antitermination
GO:0032784	regulation of DNA-templated transcription elongation
GO:0036460	cellular response to cell envelope stress
GO:0042128	nitrate assimilation
GO:0044780	bacterial-type flagellum assembly
GO:0048870	cell motility
GO:0065003	protein-containing complex assembly
GO:0071973	bacterial-type flagellum-dependent cell motility
GO:0090605	submerged biofilm formation
GO:2000142	regulation of DNA-templated transcription initiation

	Cellular Component
GO:0000345	cytosolic DNA-directed RNA polymerase complex
GO:0000428	DNA-directed RNA polymerase complex
GO:0005829	cytosol
GO:0008023	transcription elongation factor complex
GO:0030880	RNA polymerase complex

External links

PDB	RCSB:8fvw, PDBe:8fvw, PDBj:8fvw
PDBsum	8fvw
PubMed	36997761
UniProt	P0A800\|RPOZ_ECOLI DNA-directed RNA polymerase subunit omega (Gene Name=rpoZ)