Structure of PDB 8dw6 Chain H

Receptor sequence
>8dw6H (length=322) Species: 2681598 (Escherichia phage T4) [Search protein sequence]
SIPWIDNEFAYRALAHLPKFTQVNNSSTFKLRFRCPVCGDSKTDQNKARG
WYYGDNNEGNIHCYNCNYHAPIGIYLKEFEPDLYREYIFEIRKEKKKIIK
SLPSCVRLDKLAEDHPIIKYVKARCIPKDKWKYLWFTTEWPKLVNSIAPG
TYKKEISEPRLVIPIYNANGKAESFQGRALKKDAPQKYITIEAYPEATKI
YGVERVKDGDVYVLEGPIDSLFIENGIAITGGQLDLEVVPFKDRRVWVLD
NEPRHPDTIKRMTKLVDAGERVMFWDKSPWKSKDVNDMIRKEGATPEQIM
EYMKNNIAQGLMAKMRLSKYAK
3D structure
PDB8dw6 Structural basis of the T4 bacteriophage primosome assembly and primer synthesis.
ChainH
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna H W53 Y55 N58 H64 Y66 H71 W51 Y53 N56 H62 Y64 H69
BS02 ZN H C37 C40 C65 C68 C35 C38 C63 C66
Gene Ontology
Molecular Function
GO:0003896 DNA primase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006269 DNA replication, synthesis of primer
GO:0039693 viral DNA genome replication

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8dw6, PDBe:8dw6, PDBj:8dw6
PDBsum8dw6
PubMed37474605
UniProtP04520|PRIM_BPT4 DNA primase (Gene Name=61)

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