Structure of PDB 8dgw Chain H

Receptor sequence

>8dgwH (length=213) Species: 9606 (Homo sapiens) [Search protein sequence]

QVQLVQSGTEVRQPGASVRVSCKASGYTFTDSYIHWVRQAPGQGLEWMGI
IKPSGGNTRYAQRFQGRVTMTRDTSTSTVYMELSSLRSEDTAVYYCARDS
RGPGIFWGQGTLVTVSSASTKGPSVFPLAPSSKGTAALGCLVKDYFPEPV
TVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNH
KPSNTKVDKRVEP

3D structure

PDB

8dgw Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease.

Chain

Resolution

2.81 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	H	Y33 K52 N56 R58 D95 R97 G98	Y33 K52 N57 R59 D99 R101 G102
BS02	peptide	H	D31 S32 Y33 R97	D31 S32 Y33 R101

External links

PDB	RCSB:8dgw, PDBe:8dgw, PDBj:8dgw
PDBsum	8dgw
PubMed	36889306

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