Structure of PDB 8d3a Chain H

Receptor sequence

>8d3aH (length=227) Species: 9606 (Homo sapiens) [Search protein sequence]

EVQLLESGGGLVQPGGSLKLSCAASGFAVNNYPMNWVRQAPGKGLEWVSS
IIGSGSRASYADSVKGRFTISRDNGKDIVYLQMNNLRADDTALYYCVKDS
STAWWDKPAASEFDFWGQGTMVTVSSASTKGPSVFPLAPSSKSTSGGTAA
LGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSS
SLGTQTYICNVNHKPSNTKVDKRVEPK

3D structure

PDB

8d3a Analysis of two cooperating antibodies unveils immune pressure imposed on HIV Env to elicit a V3-glycan supersite broadly neutralizing antibody lineage.

Chain

Resolution

2.9 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	BMA	H	N30 W105	N30 W105
BS02	MAN	H	A28 V29 N30 N74 D77	A28 V29 N30 N74 D77
BS03	MAN	H	N74 W105	N74 W105

External links

PDB	RCSB:8d3a, PDBe:8d3a, PDBj:8d3a
PDBsum	8d3a
PubMed	36225920

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