Structure of PDB 8che Chain H

Receptor sequence

>8cheH (length=214) Species: 9606 (Homo sapiens) [Search protein sequence]

EVQLVESGGGLVQPGGSLRLSCAASGFTFSRYWMTWVRQAPGKGLVWVGE
INPDSSTINYAPSVKGRFTISRDNAKNTLYLQMNSLRAEDTAVYYCASGV
FTSWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEP
VTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVD
HKPSNTKVDKRVES

3D structure

PDB

8che HMB-001: A Novel Bispecific Antibody Accumulating and Targeting Endogenous FVIIa to Activated Platelets for Subcutaneous Prophylaxis in Multiple Bleeding Disorders Including Glanzmann Thrombasthenia.

Chain

Resolution

1.49 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	H	V2 F27 Y32 W33 E50 V100 T102	V2 F27 Y32 W33 E50 V100 T102

External links

PDB	RCSB:8che, PDBe:8che, PDBj:8che
PDBsum	8che
PubMed	39196196

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