Structure of PDB 8b9z Chain H

Receptor sequence
>8b9zH (length=315) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
MFYMEFILSLIGSLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGLM
GIPQPFCDAIKLFTKEQTYPLLSNYLSYYISPIFSLFLSLFVWMCMPFFV
KLYSFNLGGLFFLCCTSLGVYTVMVAGWSSNSNYALLGGLRAVAQTISYE
VSLALILLSFIFLIGSYNMIYFFFYQVYMWFLIILFPMALVWVSISLAET
NRTPFDFAEGESELVSGFNVEYSSGGFALIFMAEYASILFMSMLFCVIFL
GCDVFNLLFYMKLTFISFVFIWVRGTLPRFRYDKLMYLAWKCFLSFSLNY
LLFFIGFKILLFSLL
3D structure
PDB8b9z Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster.
ChainH
Resolution3.28 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating).
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 UQ9 H T28 R32 F56 D58 A59 I60 L62 F231 M232 T28 R32 F56 D58 A59 I60 L62 F231 M232
Gene Ontology
Molecular Function
GO:0003954 NADH dehydrogenase activity
GO:0008137 NADH dehydrogenase (ubiquinone) activity
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0009060 aerobic respiration
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0045271 respiratory chain complex I

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8b9z, PDBe:8b9z, PDBj:8b9z
PDBsum8b9z
PubMed36622099
UniProtP18929|NU1M_DROME NADH-ubiquinone oxidoreductase chain 1 (Gene Name=mt:ND1)

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