Structure of PDB 8acf Chain H

Receptor sequence

>8acfH (length=219) Species: 9606 (Homo sapiens) [Search protein sequence]

EVQLVQSGAEVKKPGASVKVSCKASGYTFTDYNMDWVRQATGQGLEWIGD
INPNYESTGYNQKFKGRATMTVDKSISTAYMELSSLRSEDTAVYYCARED
DHDAFAYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDY
FPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYI
CNVNHKPSNTKVDKKVEPK

3D structure

PDB

8acf Structure-function analysis of ARGX-117, a calcium- and pH-dependent clinical phase complement C2 blocking antibody

Chain

Resolution

1.8 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CA	H	E99 D103	E99 D103

External links

PDB	RCSB:8acf, PDBe:8acf, PDBj:8acf
PDBsum	8acf
PubMed

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